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20Jul

Could there be a cure for peanut and dairy allergy? Those of us with one or multiple allergies often dream of a world where our allergies could be cured forever but it’s a long way off.

We all know that there are a myriad of tiny things that can help stabilise and improve life for people with eczema, asthma and allergies, but there isn’t a cure. Desensitisation can offer hope to a handful of allergic kids at at Cambridge hospital; it’s amazing what they have done but realistically this treatment is a long way off for the masses of people with life threatening allergies out there. One day there may be treatment on the NHS to densenitise allergic kids and adults but not for many years or further testing.

Could there be a peanut and milk allergy patch?

Maybe it’s not so far off. A company called DBV Technologies, a French biotech company are developing an allergy treatment patch called Viaskin for milk and peanut allergies. The company has announced it completed Phase I of its trial for Viaskin Milk and is awaiting protocol approval from regulators to begin Phase II.

DBV Technologies’ trial, the Viaskin MILk Efficacy and Safety Phase I/II study (MILES), began in November 2014 with its first patient. The trial was designed to test the safety and efficacy of Viaskin Milk for patients allergic to cow’s milk protein between the ages of two to 17.

The Data Safety Monitoring Board for the trial recommended continuation of the study and indicated it has no concerns following evaluation of data from Phase I. Phase II of this two part trial will launch later this year pending review of Phase I data by the U.S. Food & Drug Administration and approval by U.S. and Canadian regulators of a revised trial protocol.

The allergy treatment being administered as part of this trial is unique to DBV Technologies—the company has developed a patch it calls Viaskin to desensitize patients to allergens using a proprietary immunotherapy method called epicutaneous immunotherapy. Using the Viaskin patch, allergens can enter the immune system without entering the bloodstream, reducing the occurrence of severe allergic reactions.

This clinical trial for Viaskin Milk combines phases I and II—it is being conducted just in the U.S. and Canada and it includes children as young as two years of age. To give you some context for the significance of this particular allergy, a milk allergy is the first to be developed in infancy and the most common for babies and young children: approximately 2-3% of the general population is affected by this allergy.

DBV Technologies’ other patch in development, Viaskin Peanut, is expected to go into Phase III of its clinical trial in the fourth quarter of 2015.

Getting rid of allergies for good…

Could there really be a patch that could cure peanut and dairy allergies? Could your allergy to milk be a thing of the past?

Could we really see the back of life threatening allergies and anaphylaxis for good?

We can dream about a life freefrom allergies but I do suspect it’s a long way off just yet. But maybe, just maybe, in my lifetime, it could just happen. This kind of research gives us all hope.

You can find out more about the peanut and milk patch trial here.

  

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