I'd like to add my thanks, particularly to Dr Shepherd who answered several questions from me and who has been working very hard! It's clear from the fact that the forum had to be shut down for a while because of the overwhelming number of questions that there's a huge amount of unmet clinical need ...

Hi Dr Shepherd - About 20 years ago a Professor Vijay Kakkar published a protocol for using cold baths as a therapy for ME in a newspaper. Lots of people were trying it and he had said that he was going to recruit thousands of people (not just with ME, perhaps) for a trial. I tried it myself and had...

Professor Julia Newton's team found that muscle tissue grown from biopsies taken from ME patients and subjected to electrical impulses to mimic exercise produced 10 times as much lactic acid as muscle cultured from healthy people. Obviously there's no 'perception' going on there because there's no b...

Thank you. I'll print off your reply and take it to the consultant.

Do you have any view on treating adrenal fatigue with supplements, 'adaptogen' herbs and so on?

Although I've repeatedly been diagnosed over the years with ME (narrowly defined, not just the Oxford criteria), an infectious disease consultant recently suggested that my symptoms might be due to adrenal fatigue. Having read up on it, I recognise some of the symptoms. However, other people with ME...

Hi Dr Shepherd – as you know, a trial of the immune drug Rituximab was found to show major to moderate improvement in 67% of patients with ME vs 15% of controls in a placebo-controlled, randomised trial conducted in Norway and published in 2011. According to a Norwegian TV news report, the same team...