Seizures and body locking are commonplace in SEVERE ME. There is nothing psychological about them whatsoever. When a virus migrates out of the blood and into the brain it can cause such symptoms. I believe Dan Peterson and Ian Lipkin are doing spinal fluid studies. You may find this article helpful ...

I found pregabalin much better than gabapentin.

Also magnesium malate is a great pain reliever.

Ah now many people find that B12 injections alone are not beneficial, B12 alone isn't enough if your body is not methylating, i.e converting methione into homocystine. I found hydroxy injections pretty pointless so I started supplementing with subligual methylcobalamin then I added in hydroxy at a l...

Yep. My period kill me and not softly, each month. I start getting symptoms around 5 days before my pill finishes, like every ME symptom is exacerbated times ten, I go gray, my BP drops and I cannot move and I ache and ache all over. The actual period itself is agonising. I suspect my hormones may b...