Gene editing research for EI
Posted: Thu May 12, 2022 10:22 am
In 2019, Oliver March and Julia Reichelt published a paper on the potential use of TALENS to correct the dominant KRT10 mutation in EI. Since then, both have moved onto other endeavours, and it appears that there is currently no active pre-clinical research for EI. Dr Amy Paller also explored gene editing for EI back in 2012, but has since stated that the method was never going to be a viable clinical option because of the immense time required per patient. She stated new advances in CRISPR/TALEN technology are needed in order to make gene editing an option for EI.
My question is, is there anyone in the world currently working on a gene editing solution for EI? If not, how can we move this important work forwards?
My question is, is there anyone in the world currently working on a gene editing solution for EI? If not, how can we move this important work forwards?