Ectopic pregnancy IVF and coeliac disease

[mira_falls]

Hi

I have just received a positive blood test for the autoimmune disorder called coeliac disease. I have had few symptoms apart from fertility issues and my mam is a coeliac. This is said to affect fertility including recurrent miscarriages. I have had problems conceiving and when I did after 18 months of trying it was sadly an ectopic pregnancy resulting in tubal loss.

We have been trying for another 13 months and have now started IVF with egg collection booked for 2nd April all being well. I am 37 but started trying at 34.

Husbands sperm result was 104 mill per ml, 8 % norm forms and 59% motility ( told normal). I have had normal LH, oestrogen and FSH readings but progesterone found to sometimes drop a little early so given cyclogest pessaries. My AMH reading has been 7.9 a couple of month ago which concerns me since I have discovered that coeliac disease sometimes results in earlier menopause. Judging by temps and blood results I am ovulating. We are both of healthy weight and lifestyle - husband is also 37.

I would like help with the following:

1)is any research to suggest that coeliac disease can result in ectopic pregnancy? As I did not have any of the usual reasons why an ectopic occurs.
2) a biopsy is required to diagnose fully coeliac disease but as IVF is coming up my preferred option is to go straight onto a gluten free diet to give me the best chance in IVF. To have an accurate biopsy I am told you need to include gluten in your diet. Can you see an issue with me deferring the biopsy until after IVF and hopefully a baby? I am going to seek dietician advice to ensure balanced gluten free diet and already taking pre conception vitamins
3) any ideas on any other problems can foresee on likelihood of conception from info provided?
Any help would be much appreciated

[Mr. Hugh Byrne, MRCOG]

It's unlikely that the coeliac disease caused the ectopic pregnancy. As you are now already on the IVF pathway, I'd continue the gluten free diet and proceed witht the IVF. The coeliac disease, with good diet, is unlikely to impact on the pregnancy (unless you have other autoimune conditions such as those affecting the thyroid, blood clotting ability or joints/skin etc, but these can be picked up with blood tests).

[mira_falls]

Thank you for your reply it is much appreciated. I managed to get an early endoscopy procedure yesterday and informed coeliac disease highly likely but 2 weeks for definitive results.

Can AMH levels be improved with the introduction of a gluten free diet or once they deteriorate is there no going back?

Thanks for advice